Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | KAT8 | Q9H7Z6 | 4/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 3/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | BID | P55957 | 3/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.41 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.41 |
| ▸ | EP300 | Q09472 | 1/20 | 0.41 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.41 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.41 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.41 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11770518 | 1.00 | THRA (0.51) | THRATHRBNPSR1KAT8HSP90AA1 | |
| SCHEMBL11769227 | 0.90 | CNR1 (0.52) | THRATHRBNPSR1KAT8CNR1 | |
| SCHEMBL11770385 | 0.90 | CNR1 (0.52) | THRATHRBNPSR1KAT8CNR1 | |
| SCHEMBL11770381 | 0.89 | THRA (0.47) | THRATHRBNPSR1KAT8PPARA | |
| SCHEMBL11769224 | 0.89 | THRA (0.47) | THRATHRBNPSR1KAT8PPARA | |
| SCHEMBL11771157 | 0.86 | KAT8 (0.60) | THRATHRBKAT8PPARAPPARG | |
| SCHEMBL9807232 | 0.86 | NPSR1 (0.53) | THRATHRBNPSR1KAT8PPARA | |
| SCHEMBL78018 | 0.83 | THRA (0.60) | THRATHRBKAT8PPARAPPARG | |
| SCHEMBL2804125 | 0.83 | THRA (0.60) | THRATHRBKAT8PPARAPPARG | |
| SCHEMBL30431680 | 0.83 | THRA (0.60) | THRATHRBKAT8PPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4049678-A | PROSTAGLANDINS | THE UPJOHN COMPANY (US) | 1977-09-20 | — | — | US | disclosed |