Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.59 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.54 |
| ▸ | PTGFR | P43088 | 1/20 | 0.54 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.54 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.52 |
| ▸ | PPARG | P37231 | 7/20 | 0.52 |
| ▸ | PPARD | Q03181 | 7/20 | 0.52 |
| ▸ | PPARA | Q07869 | 7/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.52 |
| ▸ | TSHR | P16473 | 4/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | TLR2 | O60603 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | FABP4 | P15090 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.52 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | ESR1 | P03372 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9623088 | 1.00 | ALOX5 (0.59) | ALOX5TBXA2RPTGFRPTGER2GPR84 | |
| SCHEMBL11039601 | 1.00 | ALOX5 (0.59) | ALOX5TBXA2RPTGFRPTGER2GPR84 | |
| Rosaprostol SCHEMBL186775 | 1.00 | ALOX5 (0.59) | ALOX5TBXA2RPTGFRPTGER2GPR84 | |
| SCHEMBL11186080 | 1.00 | ALOX5 (0.59) | ALOX5TBXA2RPTGFRPTGER2GPR84 | |
| Rosaprostol SCHEMBL186776 | 1.00 | ALOX5 (0.59) | ALOX5TBXA2RPTGFRPTGER2GPR84 | |
| Rosaprostol SCHEMBL1231120 | 0.98 | ALOX5 (0.58) | ALOX5TBXA2RPTGFRPTGER2GPR84 | |
| SCHEMBL11729161 | 0.92 | KMT2A (0.54) | ALOX5TBXA2RPTGFRPTGER2GPR84 | |
| SCHEMBL11655265 | 0.92 | KMT2A (0.54) | ALOX5TBXA2RPTGFRPTGER2GPR84 | |
| SCHEMBL9808452 | 0.91 | ALOX5 (0.56) | ALOX5TBXA2RPTGFRPTGER2GPR84 | |
| SCHEMBL9808378 | 0.91 | ALOX5 (0.56) | ALOX5TBXA2RPTGFRPTGER2GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4046787-A | ANTIULCER AGENTS | AMERICAN CYANAMID COMPANY (US) | 1977-09-06 | — | — | US | disclosed |
| US-3932472-A | INHIBITORS OF GASTRIC ACID SECRETION | AMERICAN CYANAMID COMPANY (US) | 1976-01-13 | — | — | US | disclosed |