Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 7/20 | 0.61 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.49 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.48 |
| ▸ | TTR | P02766 | 3/20 | 0.45 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11771255 | 0.94 | LTB4R (0.53) | LTB4RS1PR3AKR1B1TTRLTB4R2 | |
| SCHEMBL11765899 | 0.92 | LTB4R (0.61) | LTB4RS1PR3AKR1B1TTRLTB4R2 | |
| SCHEMBL11766632 | 0.92 | LTB4R (0.61) | LTB4RS1PR3AKR1B1TTRLTB4R2 | |
| SCHEMBL11765833 | 0.92 | LTB4R (0.61) | LTB4RS1PR3AKR1B1TTRLTB4R2 | |
| SCHEMBL11789694 | 0.92 | LTB4R (0.61) | LTB4RS1PR3AKR1B1TTRLTB4R2 | |
| SCHEMBL11774344 | 0.92 | LTB4R (0.61) | LTB4RS1PR3AKR1B1TTRLTB4R2 | |
| SCHEMBL11767398 | 0.91 | LTB4R (0.60) | LTB4RS1PR3AKR1B1TTRLTB4R2 | |
| SCHEMBL11769474 | 0.91 | LTB4R (0.60) | LTB4RS1PR3AKR1B1TTRLTB4R2 | |
| SCHEMBL11766812 | 0.90 | LTB4R (0.59) | LTB4RS1PR3AKR1B1TTRLTB4R2 | |
| SCHEMBL11767628 | 0.90 | AKR1B1 (0.52) | LTB4RAKR1B1TTRLTB4R2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3989721-A | Disubstituted xanthone carboxylic acid compounds | SYNTEX (U.S.A.) INC. (US) | 1976-11-02 | — | — | US | disclosed |
| US-3989720-A | Disubstituted xanthone carboxylic acid compounds | SYNTEX (U.S.A.) INC. (US) | 1976-11-02 | — | — | US | disclosed |
| US-3988352-A | Disubstituted xanthone carboxylic acid compounds | SYNTEX (U.S.A.) INC. (US) | 1976-10-26 | — | — | US | disclosed |
| US-3979414-A | Disubstituted xanthone carboxylic acid compounds | SYNTEX (U.S.A.) INC. (US) | 1976-09-07 | — | — | US | disclosed |
| US-3965115-A | Disubstituted xanthone carboxylic acid compounds | SYNTEX (U.S.A.) INC. (US) | 1976-06-22 | — | — | US | disclosed |
| US-3963753-A | Disubstituted xanthone carboxylic acid compounds | SYNTEX (U.S.A.) INC. (US) | 1976-06-15 | — | — | US | disclosed |
| US-3963752-A | Disubstituted xanthone carboxylic acid compounds | SYNTEX (U.S.A.) INC. (US) | 1976-06-15 | — | — | US | disclosed |