Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 1/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.48 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.48 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.47 |
| ▸ | NMUR2 | Q9GZQ4 | 9/20 | 0.47 |
| ▸ | NMUR1 | Q9HB89 | 8/20 | 0.47 |
| ▸ | CTSK | P43235 | 4/20 | 0.46 |
| ▸ | CTSL | P07711 | 2/20 | 0.46 |
| ▸ | CTSS | P25774 | 2/20 | 0.46 |
| ▸ | CTSD | P07339 | 1/20 | 0.44 |
| ▸ | CTSE | P14091 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11773078 | 1.00 | REN (0.51) | RENADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL11774767 | 0.97 | REN (0.52) | RENCTSKCTSLCTSS | |
| SCHEMBL11773127 | 0.96 | NMUR2 (0.48) | RENADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL11772364 | 0.94 | NPY1R (0.47) | RENNMUR2NMUR1 | |
| SCHEMBL11772396 | 0.94 | NPY1R (0.47) | RENNMUR2NMUR1 | |
| SCHEMBL11774056 | 0.91 | F2 (0.48) | RENNMUR2NMUR1CTSDCTSE | |
| SCHEMBL11774028 | 0.91 | F2 (0.48) | RENNMUR2NMUR1CTSDCTSE | |
| SCHEMBL11773038 | 0.89 | REN (0.47) | RENNMUR2NMUR1 | |
| SCHEMBL11771237 | 0.89 | NMUR2 (0.49) | RENNMUR2NMUR1 | |
| SCHEMBL11773146 | 0.88 | NMUR2 (0.49) | RENNMUR2NMUR1CTSDCTSE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3960828-A | Catalytic hydrogenolysis of protected sulfur containing peptides | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH, EDUCATION AND WELFARE (US) | 1976-06-01 | — | — | US | disclosed |