Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 2/20 | 0.38 |
| ▸ | GOPC | Q9HD26 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.34 |
| ▸ | FLT1 | P17948 | 1/20 | 0.34 |
| ▸ | LTK | P29376 | 1/20 | 0.34 |
| ▸ | GRK5 | P34947 | 1/20 | 0.34 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.34 |
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.34 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.34 |
| ▸ | CDK8 | P49336 | 1/20 | 0.34 |
| ▸ | GSK3A | P49840 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9450314 | 0.74 | FNTA (0.33) | KDM4ERAB9A | |
| SCHEMBL8532632 | 0.69 | FNTA (0.40) | CFTRGOPCKMT2AALDH1A1NPC1 | |
| SCHEMBL3622425 | 0.69 | ANPEP (0.41) | — | |
| SCHEMBL10738472 | 0.69 | ANPEP (0.41) | — | |
| SCHEMBL10738466 | 0.69 | ANPEP (0.41) | — | |
| Biphenyl SCHEMBL28193785 | 0.68 | TDP1 (0.42) | CFTRGOPCKMT2ACTRCALDH1A1 | |
| SCHEMBL5909229 | 0.68 | FNTA (0.33) | KDM4ERAB9A | |
| SCHEMBL11775888 | 0.68 | MMP3 (0.42) | CFTRGOPCKMT2AALDH1A1MEN1 | |
| SCHEMBL11776562 | 0.66 | FNTA (0.33) | — | |
| SCHEMBL7192053 | 0.66 | CFTR (0.35) | CFTRGOPCKMT2APTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3972901-A | Diels-Alder type process involving a geminal-dihalocyclopropane and a dienophile | ETHYL CORPORATION (US) | 1976-08-03 | — | — | US | claimed |