Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 11/20 | 0.52 |
| ▸ | CNR1 | P21554 | 11/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.44 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.44 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.44 |
| ▸ | TRPV2 | Q9Y5S1 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11733885 | 0.80 | CNR2 (0.58) | CNR2CNR1OPRM1TRPA1CYP1A1 | |
| SCHEMBL11780197 | 0.80 | CNR2 (0.59) | CNR2CNR1OPRM1TRPA1CYP1A1 | |
| SCHEMBL11775042 | 0.79 | CNR2 (0.40) | CNR2CNR1 | |
| SCHEMBL11774390 | 0.79 | PTPN1 (0.36) | CNR2CNR1PTPN1 | |
| SCHEMBL11771325 | 0.76 | CNR2 (0.48) | CNR2CNR1OPRM1TRPA1CYP1A1 | |
| SCHEMBL11773119 | 0.76 | CNR2 (0.47) | CNR2CNR1OPRM1TRPA1CYP1A1 | |
| SCHEMBL10989218 | 0.73 | ALDH1A1 (0.60) | CNR2CNR1OPRM1TRPA1CYP1A1 | |
| SCHEMBL11779094 | 0.72 | CNR2 (0.56) | CNR2CNR1OPRM1TRPA1CYP1A1 | |
| SCHEMBL11738376 | 0.72 | CNR2 (0.67) | CNR2CNR1OPRM1TRPA1CYP1A1 | |
| SCHEMBL11739308 | 0.72 | CNR2 (0.72) | CNR2CNR1OPRM1TRPA1CYP1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4051152-A | TRANQUILIZERS, ANALGESICS | SHARPS ASSOCIATES (US) | 1977-09-27 | — | — | US | disclosed |