Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | PYGM | P11217 | 2/20 | 0.47 |
| ▸ | PYGL | P06737 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | STAT1 | P42224 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13777318 | 0.84 | CYP2C19 (0.60) | HSD17B10ALOX15MAPK1CYP2C19POLB | |
| SCHEMBL11284057 | 0.82 | ALDH1A1 (0.58) | HSD17B10ALOX15POLBKDM4EALDH1A1 | |
| SCHEMBL29204714 | 0.82 | ALDH1A1 (0.58) | HSD17B10ALOX15POLBKDM4EALDH1A1 | |
| SCHEMBL25063290 | 0.80 | HSD17B10 (0.58) | HSD17B10ALOX15MAPK1CYP2C19POLB | |
| SCHEMBL25063289 | 0.79 | HPGD (0.56) | HSD17B10ALOX15MAPK1CYP2C19POLB | |
| SCHEMBL25063171 | 0.79 | HPGD (0.56) | HSD17B10ALOX15MAPK1CYP2C19POLB | |
| SCHEMBL25063444 | 0.79 | SMN1; SMN2 (0.58) | HSD17B10ALOX15MAPK1CYP2C19POLB | |
| SCHEMBL11774032 | 0.79 | KMT2A (0.59) | ALOX15MAPK1POLBKDM4EALDH1A1 | |
| SCHEMBL110042 | 0.77 | POLB (0.72) | HSD17B10CYP2C19POLBKDM4EALDH1A1 | |
| SCHEMBL29437050 | 0.77 | POLB (0.72) | HSD17B10CYP2C19POLBKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3932419-A | QUINOLINE DYES | BAYER AKTIENGESELLSCHAFT (DT) | 1976-01-13 | — | — | US | disclosed |