Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 3/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.51 |
| ▸ | UTS2R | Q9UKP6 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ACE | P12821 | 4/20 | 0.45 |
| ▸ | ITGB1 | P05556 | 3/20 | 0.45 |
| ▸ | ITGAV | P06756 | 1/20 | 0.45 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.45 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.44 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.43 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | ACACB | O00763 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11778492 | 0.92 | HRH3 (0.53) | ITGB3ITGA2BGAARAB9AACE | |
| SCHEMBL11776877 | 0.90 | ITGB3 (0.50) | ITGB3ITGA2BGAARAB9AACE | |
| SCHEMBL11780603 | 0.90 | ITGB3 (0.50) | ITGB3ITGA2BGAARAB9AACE | |
| SCHEMBL11777095 | 0.90 | ITGB3 (0.50) | ITGB3ITGA2BGAARAB9AACE | |
| SCHEMBL11777398 | 0.89 | MCHR1 (0.49) | ITGB3ITGA2BGAARAB9AACE | |
| SCHEMBL11775291 | 0.89 | ITGB3 (0.52) | ITGB3ITGA2BGAARAB9AACE | |
| SCHEMBL11779017 | 0.85 | ITGB1 (0.42) | ITGB3ITGA2BUTS2RACEITGB1 | |
| SCHEMBL11778117 | 0.85 | ABCG2 (0.46) | ITGB3ITGA2BRAB9AHRH3 | |
| SCHEMBL11779137 | 0.82 | GRIA1 (0.59) | ACEL3MBTL1 | |
| SCHEMBL11777894 | 0.82 | GRIA1 (0.59) | ACEL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4004008-A | ANTISPASMODIC, VASODILATION | ROTTA RESEARCH LABORATORIUM S.P.A. (IT) | 1977-01-18 | — | — | US | disclosed |