Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | UGT2B7 | P16662 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11803288 | 0.75 | — | — | |
| SCHEMBL27515678 | 0.74 | TSHR (0.34) | TSHRNFKB1CYP2C19 | |
| SCHEMBL7979935 | 0.74 | — | — | |
| SCHEMBL9786341 | 0.72 | TSHR (0.43) | TSHRNFKB1CYP2C19 | |
| SCHEMBL10763467 | 0.72 | TSHR (0.43) | TSHRNFKB1CYP2C19 | |
| SCHEMBL9192258 | 0.70 | TSHR (0.38) | TSHRNFKB1CYP2C19 | |
| SCHEMBL374945 | 0.67 | TSHR (0.39) | TSHRNFKB1CYP2C19 | |
| SCHEMBL11548298 | 0.67 | TSHR (0.39) | TSHRNFKB1CYP2C19UGT2B7 | |
| SCHEMBL8090265 | 0.66 | TSHR (0.37) | TSHRNFKB1CYP2C19 | |
| SCHEMBL27961792 | 0.65 | TSHR (0.57) | TSHRNFKB1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4001189-A | Fibers of acid-dyeable polyester having tetramethylpiperidine groups attached through oxyalkalene linkages to ends of polymer chains | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1977-01-04 | — | — | US | claimed |
| US-3974127-A | Alkylene oxide condensates of tetramethylpiperidine alcohols or glycols | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1976-08-10 | — | — | US | claimed |
| US-3974127-A | Alkylene oxide condensates of tetramethylpiperidine alcohols or glycols | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1976-08-10 | — | — | US | disclosed |