Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 4/20 | 0.54 |
| ▸ | ITGA4 | P13612 | 4/20 | 0.54 |
| ▸ | ITGB7 | P26010 | 4/20 | 0.54 |
| ▸ | GRIA1 | P42261 | 8/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.47 |
| ▸ | CHRNG | P07510 | 1/20 | 0.47 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.47 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.47 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.47 |
| ▸ | CHRND | Q07001 | 1/20 | 0.47 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.47 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11779711 | 0.82 | ACE (0.46) | GRIA1CHRNA1CHRNGCHRNB1CHRNB2 | |
| SCHEMBL11779137 | 0.78 | GRIA1 (0.59) | GRIA1 | |
| SCHEMBL11777894 | 0.78 | GRIA1 (0.59) | GRIA1 | |
| SCHEMBL8297700 | 0.76 | ITGB1 (0.56) | ITGB1ITGA4ITGB7 | |
| SCHEMBL5629458 | 0.76 | ITGB1 (0.56) | ITGB1ITGA4ITGB7 | |
| SCHEMBL11774786 | 0.76 | GRIA1 (0.47) | GRIA1CHRNA1CHRNGCHRNB1CHRNB2 | |
| SCHEMBL11777896 | 0.76 | GRIA1 (0.47) | GRIA1CHRNA1CHRNGCHRNB1CHRNB2 | |
| SCHEMBL24862961 | 0.73 | GFER (0.58) | ITGB1ITGA4ITGB7 | |
| SCHEMBL11776373 | 0.72 | GRIA1 (0.47) | GRIA1CHRNA1CHRNGCHRNB1CHRNB2 | |
| SCHEMBL11777557 | 0.72 | CHRND (0.56) | GRIA1CHRNA1CHRNGCHRNB1CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4004008-A | ANTISPASMODIC, VASODILATION | ROTTA RESEARCH LABORATORIUM S.P.A. (IT) | 1977-01-18 | — | — | US | disclosed |