Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRND | Q07001 | 6/20 | 0.56 |
| ▸ | CHRNA1 | P02708 | 2/20 | 0.56 |
| ▸ | CHRNG | P07510 | 2/20 | 0.56 |
| ▸ | CHRNB1 | P11230 | 2/20 | 0.56 |
| ▸ | GRIA1 | P42261 | 8/20 | 0.54 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.53 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.53 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.53 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.53 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.53 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.53 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11775228 | 0.96 | GRIA1 (0.57) | CHRNDCHRNA1CHRNGCHRNB1GRIA1 | |
| SCHEMBL10543883 | 0.85 | GRIA1 (0.71) | CHRNDCHRNA1CHRNGCHRNB1GRIA1 | |
| SCHEMBL10543878 | 0.85 | GRIA1 (0.71) | CHRNDCHRNA1CHRNGCHRNB1GRIA1 | |
| SCHEMBL11775760 | 0.81 | PLG (0.46) | — | |
| SCHEMBL11796137 | 0.81 | GRIA1 (0.75) | CHRNDCHRNA1CHRNGCHRNB1GRIA1 | |
| SCHEMBL16993998 | 0.81 | PYGL (0.50) | — | |
| SCHEMBL16999320 | 0.81 | PYGL (0.50) | — | |
| SCHEMBL11779711 | 0.80 | ACE (0.46) | CHRNDCHRNA1CHRNGCHRNB1GRIA1 | |
| SCHEMBL11778440 | 0.79 | CHRND (0.57) | CHRNDCHRNA1CHRNGCHRNB1GRIA1 | |
| SCHEMBL19477908 | 0.78 | CHRND (0.61) | CHRNDCHRNA1CHRNGCHRNB1GRIA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4004008-A | ANTISPASMODIC, VASODILATION | ROTTA RESEARCH LABORATORIUM S.P.A. (IT) | 1977-01-18 | — | — | US | disclosed |