Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 7/20 | 0.56 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | DAO | P14920 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5758318 | 0.81 | TAAR1 (0.41) | TAAR1RAB9ATSHRSMN1; SMN2NPC1 | |
| SCHEMBL3979810 | 0.81 | MAOB (0.43) | TAAR1RAB9ASMN1; SMN2NPC1CYP2D6 | |
| SCHEMBL16313542 | 0.81 | NPC1 (0.53) | TAAR1RAB9ASMN1; SMN2NPC1CYP2D6 | |
| SCHEMBL8112160 | 0.81 | TAAR1 (0.41) | TAAR1RAB9ATSHRSMN1; SMN2NPC1 | |
| SCHEMBL11581355 | 0.81 | TAAR1 (0.53) | TAAR1TSHRSMN1; SMN2CYP2D6LMNA | |
| SCHEMBL3979574 | 0.80 | SMN1; SMN2 (0.58) | TAAR1RAB9ATSHRSMN1; SMN2NPC1 | |
| SCHEMBL8108136 | 0.80 | TAAR1 (0.41) | TAAR1RAB9ATSHRSMN1; SMN2NPC1 | |
| SCHEMBL7508077 | 0.79 | TAAR1 (0.42) | TAAR1RAB9ATSHRSMN1; SMN2NPC1 | |
| SCHEMBL11760408 | 0.79 | MAOB (0.49) | TAAR1RAB9ASMN1; SMN2MAOBLMNA | |
| SCHEMBL11702882 | 0.79 | TAAR1 (0.73) | TAAR1RAB9ATSHRSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4086242-B1 | 5-[(2,4-DINITROPHENOXY)METHYL]-1-METHYL-2-NITRO-L H-IMIDAZOLE AND ITS PHARMACEUTICAL USE | RIVUS PHARMACEUTICALS INC (US) | 2026-04-08 | — | — | EP | disclosed |
| US-8492556-B2 | 2,5-Dioxoimidazolidin-1-yl-3-phenylurea derivatives as formyl peptide receptor like-1 (FPRL-1) receptor modulators | ALLERGAN, INC. (US) | 2013-07-23 | — | — | US | disclosed |
| CN-101421247-B | imidazole derivatives, process for their preparation and their use as medicaments | IPSEN PHARMA SAS | 2011-06-15 | — | — | CN | disclosed |
| US-7572921-B2 | Substituted benzylimidazoles useful for the treatment of inflammatory diseases | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-08-11 | — | — | US | disclosed |
| CN-101421247-A | Novel imidazole derivatives, process for their preparation and their use as medicaments | SOD CONSEILS RECH APPLIC (FR) | 2009-04-29 | — | — | CN | disclosed |
| CN-1795179-A | Novel imidazole derivatives, the production thereof, and the use of the same as a medicament | SOD CONSEILS RECH APPLIC (FR) | 2006-06-28 | — | — | CN | disclosed |
| CN-1477960-A | EPA receptor inhibitors to treat rheumatoid arthritis | — | 2004-02-25 | — | — | CN | disclosed |
| US-4031232-A | 1-Alkyl-2-(phenoxymethyl)-5-nitro-imidazoles and process for their manufacture | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-06-21 | — | — | US | disclosed |