SCHEMBL3979574

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL8108136	0.81	TAAR1 (0.41)	SMN1; SMN2ALDH1A1TP53NPC1RAB9A
	SCHEMBL11779657	0.80	TAAR1 (0.56)	SMN1; SMN2TP53NPC1RAB9AMAOB
	SCHEMBL7509515	0.79	TAAR1 (0.45)	SMN1; SMN2ALDH1A1TP53NPC1RAB9A
	SCHEMBL3171172	0.77	TAAR1 (0.61)	SMN1; SMN2HTTTAAR1MAPK1
	SCHEMBL3155807	0.76	CHRM2 (0.52)	SMN1; SMN2ALDH1A1LMNAHTTNPSR1
	SCHEMBL3155811	0.76	TAAR1 (0.65)	SMN1; SMN2LMNATAAR1TSHR
	SCHEMBL3155805	0.75	TAAR1 (0.42)	SMN1; SMN2ALDH1A1TP53NPC1RAB9A
	SCHEMBL15063375	0.74	NPC1 (1.00)	SMN1; SMN2ALDH1A1TP53NPC1RAB9A
	SCHEMBL3155732	0.74	TAAR1 (0.67)	SMN1; SMN2LMNATAAR1ALOX15TSHR
	SCHEMBL16313542	0.73	NPC1 (0.53)	SMN1; SMN2ALDH1A1NPC1RAB9ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.