Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | JUN | P05412 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 2/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | KDM5A | P29375 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | GUSB | P08236 | 2/20 | 0.31 |
| ▸ | AURKA | O14965 | 1/20 | 0.30 |
| ▸ | KIF11 | P52732 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11782005 | 0.99 | HSD17B10 (0.48) | HSD17B10HTTHCAR2JUNNFKB1 | |
| SCHEMBL11782800 | 0.85 | HSD17B10 (0.65) | HSD17B10HTTHCAR2JUNNFKB1 | |
| Ammonia Solution, Strong SCHEMBL11782697 | 0.83 | HSD17B10 (0.63) | HSD17B10HTTHCAR2JUNNFKB1 | |
| SCHEMBL11775178 | 0.80 | HTT (0.71) | HSD17B10HTTKDM4EHPGDMAPK1 | |
| SCHEMBL11782069 | 0.79 | CNR1 (0.50) | HSD17B10HTTHCAR2JUNNFKB1 | |
| SCHEMBL3256923 | 0.74 | HTT (0.40) | HSD17B10HTTJUNNFKB1NFKB2 | |
| SCHEMBL11781877 | 0.70 | HSD17B10 (0.46) | HSD17B10HTTHCAR2KDM4EHPGD | |
| Hydrochloric Acid SCHEMBL3252443 | 0.67 | KMT2A (0.42) | HTTKDM4EHPGDMEN1LMNA | |
| SCHEMBL11772595 | 0.66 | HSD17B10 (0.43) | HSD17B10HTTKDM4EGAAHPGD | |
| SCHEMBL11800814 | 0.66 | PKM (0.71) | HSD17B10KDM4EGAAHPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3962264-A | AMMONIA, TETRA-ALKOXY-PROPANE, MALONONITRILE | PFIZER INC. (US) | 1976-06-08 | — | — | US | disclosed |
| US-3950160-A | INHIBITING THE GROWTH OF WEEDS WITH 2-SUBSTITUTED PYRDIDOPYIMIDINES AND SALTS THEREOF | PFIZER INC. (US) | 1976-04-13 | — | — | US | disclosed |