Known targets — ChEMBL curated mechanism
CHRM1CHRM2CHRM3CHRM4CHRM5SLC6A2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EEF2K | O00418 | 1/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5796045 | 0.81 | EEF2K (0.52) | EEF2KCYP2D6CYP2C19HTTSMN1; SMN2 | |
| SCHEMBL5796998 | 0.81 | EEF2K (0.52) | EEF2KCYP2D6CYP2C19HTTSMN1; SMN2 | |
| SCHEMBL5793435 | 0.81 | EEF2K (0.52) | EEF2KCYP2D6CYP2C19HTTSMN1; SMN2 | |
| SCHEMBL5793438 | 0.81 | EEF2K (0.52) | EEF2KCYP2D6CYP2C19HTTSMN1; SMN2 | |
| SCHEMBL9814357 | 0.81 | KCNH2 (0.41) | NR1I2KCNH2LMNACYP2D6CYP2C9 | |
| SCHEMBL9814361 | 0.81 | KCNH2 (0.41) | NR1I2KCNH2LMNACYP2D6CYP2C9 | |
| Water SCHEMBL11786342 | 0.80 | EEF2K (0.51) | EEF2KCYP2D6CYP2C19HTTSMN1; SMN2 | |
| Iodide SCHEMBL11780581 | 0.80 | EEF2K (0.55) | EEF2KCYP2D6CYP2C19 | |
| Iodide SCHEMBL28957905 | 0.80 | EEF2K (0.55) | EEF2KCYP2D6CYP2C19 | |
| Hydrochloric Acid SCHEMBL2008792 | 0.80 | EEF2K (0.51) | EEF2K |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3931129-A | FLUOROELASTOMER COMPOSITION | DAIKIN KOGYO CO., LTD. (JA) | 1976-01-06 | — | — | US | disclosed |