SCHEMBL11780452

SCHEMBL11780452

CCCCCCCCCCCCN1CCN(C)C1C.Cc1ccc(S(=O)(=O)O)cc1

nearest known ligand 0.41

Known targets — ChEMBL curated mechanism

ABL1BMXBRAFBTKCHRNA4CHRNB2CSNK1EEGFRERBB2F10FLT1FLT3FLT4IGF1RINSRITKJAK3KDRKITOPRM1PARP1PARP2PDGFRBPIK3CDRAF1RETSLC18A2TECTXKdacAdacBdacCftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
OPRM1 known ✓ P35372 1/20 0.35
CYP2D6 P10635 3/20 0.41
ALDH1A1 P00352 3/20 0.39
MCHR1 Q99705 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.38
CYP1A2 P05177 1/20 0.36
THRB P10828 2/20 0.35
OPRK1 P41145 1/20 0.35
LMNA P02545 1/20 0.35
ALB P02768 1/20 0.35
CYP2C9 P11712 1/20 0.35
TSHR P16473 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
S1PR3 Q99500 1/20 0.35
CNR2 P34972 1/20 0.35
CA12 O43570 2/20 0.35
CA1 P00915 2/20 0.35
CA2 P00918 2/20 0.35
CA9 Q16790 2/20 0.35
CYP3A4 P08684 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11780791 0.85 CYP2D6 (0.38) CYP2D6ALDH1A1MCHR1L3MBTL1CYP1A2
SCHEMBL4624414 0.81 CYP2D6 (0.40) CYP2D6ALDH1A1MCHR1L3MBTL1CYP1A2
Heptane SCHEMBL8501523 0.79 MCHR1 (0.56) ALDH1A1MCHR1L3MBTL1LMNAALB
Undecane SCHEMBL28638565 0.79 MCHR1 (0.56) ALDH1A1MCHR1L3MBTL1LMNAALB
Tetradecane SCHEMBL29089041 0.79 MCHR1 (0.56) ALDH1A1MCHR1L3MBTL1LMNAALB
Decane SCHEMBL17004268 0.79 MCHR1 (0.56) ALDH1A1MCHR1L3MBTL1LMNAALB
Octane SCHEMBL356741 0.79 MCHR1 (0.56) ALDH1A1MCHR1L3MBTL1LMNAALB
Octane SCHEMBL8462698 0.79 MCHR1 (0.56) ALDH1A1MCHR1L3MBTL1LMNAALB
Dodecane SCHEMBL7126605 0.79 MCHR1 (0.56) ALDH1A1MCHR1L3MBTL1LMNAALB
Nonane SCHEMBL28716314 0.79 MCHR1 (0.56) ALDH1A1MCHR1L3MBTL1LMNAALB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3931129-A FLUOROELASTOMER COMPOSITION DAIKIN KOGYO CO., LTD. (JA) 1976-01-06 US disclosed