Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 2/20 | 0.36 |
| ▸ | NPY1R | P25929 | 1/20 | 0.30 |
| ▸ | NPY2R | P49146 | 1/20 | 0.30 |
| ▸ | NPY4R | P50391 | 1/20 | 0.30 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17635975 | 0.95 | GSR (0.41) | GSRNPY1RNPY2RNPY4RNPY5R | |
| SCHEMBL30449737 | 0.93 | GSR (0.42) | GSRNPY1RNPY2RNPY4RNPY5R | |
| SCHEMBL11128856 | 0.93 | GSR (0.42) | GSRNPY1RNPY2RNPY4RNPY5R | |
| SCHEMBL22633362 | 0.85 | TSHR (0.33) | — | |
| SCHEMBL14646342 | 0.85 | TSHR (0.33) | — | |
| SCHEMBL22653068 | 0.85 | TSHR (0.33) | — | |
| SCHEMBL18928412 | 0.83 | GSR (0.45) | GSRNPY1RNPY2RNPY4RNPY5R | |
| SCHEMBL15973213 | 0.83 | GSR (0.38) | GSRNPY1RNPY2RNPY4RNPY5R | |
| SCHEMBL22633347 | 0.80 | TSHR (0.33) | — | |
| SCHEMBL22633350 | 0.80 | TSHR (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4054594-A | Separation of diastereomers | UNIVERSITY OF CHICAGO (US) | 1977-10-18 | — | — | US | disclosed |