Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EEF2K | O00418 | 1/20 | 0.38 |
| ▸ | CCR5 | P51681 | 11/20 | 0.34 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.33 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.33 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22189075 | 0.91 | EEF2K (0.35) | EEF2KCCR5GNAI3GNAO1GNAI1 | |
| Hydrochloric Acid SCHEMBL4052333 | 0.90 | CCR5 (0.37) | EEF2KCCR5GNAI3GNAO1GNAI1 | |
| SCHEMBL5797197 | 0.80 | EEF2K (0.37) | EEF2KCCR5GNAI3GNAO1GNAI1 | |
| SCHEMBL8453756 | 0.80 | EEF2K (0.37) | EEF2KCCR5GNAI3GNAO1GNAI1 | |
| SCHEMBL28398124 | 0.80 | EEF2K (0.37) | EEF2KCCR5GNAI3GNAO1GNAI1 | |
| SCHEMBL5796690 | 0.80 | EEF2K (0.37) | EEF2KCCR5GNAI3GNAO1GNAI1 | |
| SCHEMBL5794438 | 0.80 | EEF2K (0.37) | EEF2KCCR5GNAI3GNAO1GNAI1 | |
| SCHEMBL2927391 | 0.80 | EEF2K (0.37) | EEF2KCCR5GNAI3GNAO1GNAI1 | |
| SCHEMBL6383372 | 0.80 | EEF2K (0.37) | EEF2KCCR5GNAI3GNAO1GNAI1 | |
| SCHEMBL5794615 | 0.80 | EEF2K (0.37) | EEF2KCCR5GNAI3GNAO1GNAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3931129-A | FLUOROELASTOMER COMPOSITION | DAIKIN KOGYO CO., LTD. (JA) | 1976-01-06 | — | — | US | disclosed |