Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | TP53 | P04637 | 3/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | THRB | P10828 | 3/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylic Acid Ethyl Ester SCHEMBL28234481 | 0.94 | TSHR (0.57) | TSHRHPGDALDH1A1TP53HIF1A | |
| Alcohol SCHEMBL28412104 | 0.90 | TSHR (0.59) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL117942 | 0.89 | — | — | |
| Chloromethane SCHEMBL21680132 | 0.88 | TSHR (0.56) | TSHRHPGDALDH1A1TP53HIF1A | |
| Acrylic Acid Ethyl Ester SCHEMBL3280684 | 0.88 | TSHR (0.55) | TSHRHPGDALDH1A1TP53HIF1A | |
| Hydrochloric Acid SCHEMBL1920816 | 0.87 | — | — | |
| Ammonia Solution, Strong SCHEMBL22612047 | 0.87 | — | — | |
| Bromide SCHEMBL28057371 | 0.87 | — | — | |
| Acrylic Acid Ethyl Ester SCHEMBL4377433 | 0.87 | TSHR (0.54) | TSHRHPGDALDH1A1TP53HIF1A | |
| Acrylic Acid Ethyl Ester SCHEMBL10930565 | 0.87 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4009256-A | NOVEL SHAMPOO COMPOSITION CONTAINING A WATER-SOLUBLE CATIONIC POLYMER | NATIONAL STARCH AND CHEMICAL CORPORATION (US) | 1977-02-22 | — | — | US | claimed |
| US-4038233-A | AQUEOUS RESIN COMPOSITION CONTAINING POLYMERS OR COPOLYMERS OF ETHYLENICALLY UNSATURATED MONOMERS AND A WATER-SOLUBLE CATIONIC POLYELECTROLYTE POLYMER | JOHNSON & JOHNSON (US) | 1977-07-26 | — | — | US | disclosed |