Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.60 |
| ▸ | WNT3A | P56704 | 4/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.54 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.53 |
| ▸ | CDK2 | P24941 | 1/20 | 0.53 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.53 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.51 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.49 |
| ▸ | MME | P08473 | 1/20 | 0.49 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA5A | P35218 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13329762 | 0.82 | SRC (0.52) | SRCTAAR1MEN1KMT2A | |
| SCHEMBL1177868 | 0.82 | KMT2A (0.66) | LMNAMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL254938 | 0.81 | SRC (0.90) | SRCWNT3ALMNAMEN1KMT2A | |
| SCHEMBL539023 | 0.81 | ABCC4 (0.67) | SRCTAAR1CYP17A1CYP3A4CYP11B1 | |
| Methane SCHEMBL9654819 | 0.80 | ABCC4 (0.65) | SRCWNT3ATAAR1CYP17A1CYP3A4 | |
| SCHEMBL1137228 | 0.78 | GAA (0.63) | CYP3A4LMNAMEN1KMT2AKDM4E | |
| SCHEMBL1178020 | 0.78 | CA12 (0.48) | SRCWNT3ALMNACA12CA1 | |
| SCHEMBL18381494 | 0.78 | SHMT1 (0.55) | SRCWNT3ALMNAMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL27570940 | 0.77 | GAA (0.61) | CYP3A4LMNAMEN1KMT2AKDM4E | |
| SCHEMBL9890765 | 0.77 | SMN1; SMN2 (0.43) | SRCLMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7883713-B2 | Suspension, ointment, solution, spray, lotion, gel, cream, powder, powder spray, paste, emulsion, foam or stick; for treatment of herpes infections in humans | AICURIS GMBH & CO. KG (DE) | 2011-02-08 | — | — | US | disclosed |