Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.52 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.52 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | CASP1 | P29466 | 2/20 | 0.39 |
| ▸ | CASP7 | P55210 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11776203 | 0.92 | HDAC4 (0.52) | HDAC4HDAC7HDAC5PGREGFR | |
| SCHEMBL38661846 | 0.87 | HDAC4 (0.67) | HDAC4HDAC7HDAC5EGFRSRC | |
| SCHEMBL2992029 | 0.87 | HDAC4 (0.67) | HDAC4HDAC7HDAC5EGFRSRC | |
| SCHEMBL7702581 | 0.84 | PGR (0.43) | HDAC4HDAC7HDAC5PGREGFR | |
| SCHEMBL7702518 | 0.83 | PGR (0.43) | HDAC4HDAC7HDAC5PGREGFR | |
| SCHEMBL7703633 | 0.81 | PGR (0.41) | HDAC4HDAC7HDAC5PGREGFR | |
| SCHEMBL7702521 | 0.81 | PGR (0.41) | HDAC4HDAC7HDAC5PGREGFR | |
| SCHEMBL14564636 | 0.79 | HDAC4 (0.45) | HDAC4HDAC7HDAC5PGREGFR | |
| SCHEMBL1981762 | 0.78 | HDAC3 (0.44) | HDAC4HDAC7HDAC5MEN1KMT2A | |
| SCHEMBL3772600 | 0.78 | HDAC4 (0.55) | HDAC4HDAC7HDAC5EGFRSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3979515-A | THYMOANALEPTIC ACTIVITY | ROUSSEL-UCLAF (FR) | 1976-09-07 | — | — | US | disclosed |
| US-3957757-A | THYMOANALEPTICS | ROUSSEL-UCLAF (FR) | 1976-05-18 | — | — | US | disclosed |