Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | GRN | P28799 | 1/20 | 0.42 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.42 |
| ▸ | KMO | O15229 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11785578 | 0.88 | SLC6A4 (0.50) | TSHRHSP90AA1HSP90AB1HPGDSLC6A4 | |
| SCHEMBL11785050 | 0.88 | TSHR (0.55) | TSHRHSP90AA1HSP90AB1HPGDSLC6A4 | |
| SCHEMBL27317243 | 0.88 | TSHR (0.56) | TSHRHSP90AA1HSP90AB1HPGDSLC6A4 | |
| SCHEMBL11779300 | 0.86 | TSHR (0.63) | TSHRHSP90AA1HSP90AB1HPGDSLC6A4 | |
| SCHEMBL3365999 | 0.84 | TSHR (0.52) | TSHRHSP90AA1HSP90AB1HPGDSLC6A4 | |
| SCHEMBL11782487 | 0.82 | TSHR (0.50) | TSHRHSP90AA1HSP90AB1HPGDSLC6A4 | |
| SCHEMBL11779998 | 0.78 | TSHR (0.50) | TSHRHSP90AA1HSP90AB1HPGDSLC6A4 | |
| SCHEMBL11819690 | 0.77 | TSHR (0.77) | TSHRHSP90AA1HSP90AB1HPGDSLC6A3 | |
| SCHEMBL22727569 | 0.76 | TSHR (0.43) | TSHRHSP90AA1HSP90AB1HPGDSLC6A4 | |
| SCHEMBL11783170 | 0.76 | TSHR (0.54) | TSHRHSP90AA1HSP90AB1HPGDSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3982931-A | N,N-di-sec.butyl-benzamide herbicides | MONTEDISON S.P.A. (IT) | 1976-09-28 | — | — | US | disclosed |