Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
| ▸ | GRN | P28799 | 1/20 | 0.39 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11783170 | 0.96 | TSHR (0.54) | TSHRSLC6A4SLC6A3SLC6A2KCNH2 | |
| SCHEMBL3365999 | 0.93 | TSHR (0.52) | TSHRSLC6A4SLC6A3SLC6A2KCNH2 | |
| SCHEMBL11782487 | 0.87 | TSHR (0.50) | TSHRSLC6A4SLC6A3SLC6A2KCNH2 | |
| SCHEMBL11782564 | 0.81 | SLC6A2 (0.47) | TSHRSLC6A4SLC6A3SLC6A2KCNH2 | |
| SCHEMBL11784020 | 0.80 | HSP90AA1 (0.40) | TSHRSLC6A4SLC6A3SLC6A2KCNH2 | |
| SCHEMBL11783594 | 0.80 | HPGD (0.43) | TSHRSLC6A4SLC6A3SLC6A2KCNH2 | |
| SCHEMBL11785050 | 0.79 | TSHR (0.55) | TSHRSLC6A4SLC6A3SLC6A2KCNH2 | |
| SCHEMBL11782048 | 0.78 | TSHR (0.54) | TSHRSLC6A4SLC6A3SLC6A2KCNH2 | |
| SCHEMBL11782049 | 0.77 | HSP90AA1 (0.38) | TSHRSLC6A4SLC6A3SLC6A2KCNH2 | |
| SCHEMBL11784202 | 0.77 | ALDH1A1 (0.55) | SLC6A4SLC6A3SLC6A2KCNH2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3982931-A | N,N-di-sec.butyl-benzamide herbicides | MONTEDISON S.P.A. (IT) | 1976-09-28 | — | — | US | disclosed |