Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALPL | P05186 | 3/20 | 0.40 |
| ▸ | ALPI | P09923 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.37 |
| ▸ | MGLL | Q99685 | 2/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11782878 | 1.00 | SMN1; SMN2 (0.42) | SMN1; SMN2LMNAKDM4EHTTMAPT | |
| SCHEMBL11785413 | 1.00 | SMN1; SMN2 (0.42) | SMN1; SMN2LMNAKDM4EHTTMAPT | |
| SCHEMBL11784400 | 0.88 | ALDH1A1 (0.39) | SMN1; SMN2LMNANPC1RAB9AALPL | |
| SCHEMBL25153650 | 0.82 | ALDH1A1 (0.40) | LMNAKDM4EALPLALPIALDH1A1 | |
| SCHEMBL2608960 | 0.74 | POLB (0.41) | SMN1; SMN2NPC1RAB9AALDH1A1PTGS1 | |
| SCHEMBL11782323 | 0.72 | ALDH1A1 (0.42) | LMNAL3MBTL1ALPLALPIALDH1A1 | |
| SCHEMBL11783018 | 0.72 | ALDH1A1 (0.34) | SMN1; SMN2LMNANPC1RAB9AALPL | |
| SCHEMBL11785306 | 0.72 | ALDH1A1 (0.34) | LMNAALPLALPIALDH1A1 | |
| SCHEMBL11785302 | 0.72 | ALDH1A1 (0.34) | LMNAALPLALPIALDH1A1 | |
| SCHEMBL11785233 | 0.71 | SMN1; SMN2 (0.46) | SMN1; SMN2LMNAKDM4EHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3981715-A | 2,3,5-Substituted-6-trifluoromethyl-1,3-diazin-4-ones herbicides | AMERICAN CYANAMID COMPANY (US) | 1976-09-21 | — | — | US | disclosed |