Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 9/20 | 0.57 |
| ▸ | PPARA | Q07869 | 5/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.49 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 5/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11784927 | 0.85 | FBP1 (0.65) | FBP1PPARACYP1A2ABCB11CYP3A4 | |
| SCHEMBL11784919 | 0.85 | FBP1 (0.65) | FBP1PPARACYP1A2ABCB11CYP3A4 | |
| SCHEMBL20024708 | 0.79 | FBP1 (0.75) | FBP1PPARACYP1A2ABCB11CYP3A4 | |
| SCHEMBL11785569 | 0.79 | FBP1 (0.67) | FBP1PPARACYP1A2ABCB11CYP3A4 | |
| SCHEMBL11785564 | 0.79 | FBP1 (0.67) | FBP1PPARACYP1A2ABCB11CYP3A4 | |
| SCHEMBL11738813 | 0.78 | POLB (0.58) | FBP1GSK3BL3MBTL1ALDH1A1APP | |
| SCHEMBL11784151 | 0.77 | APP (0.44) | PPARAGSK3BALDH1A1APPKDM4E | |
| SCHEMBL10348535 | 0.74 | GSK3B (0.79) | CYP1A2GSK3BL3MBTL1CYP2C19SMN1; SMN2 | |
| SCHEMBL10348536 | 0.74 | GSK3B (0.79) | CYP1A2GSK3BL3MBTL1CYP2C19SMN1; SMN2 | |
| SCHEMBL11786214 | 0.74 | MAOB (0.66) | FBP1PPARACYP1A2ABCB11CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3968117-A | CARDIOVASCULAR | BAYER AKTIENGESELLSCHAFT (DT) | 1976-07-06 | — | — | US | disclosed |
| US-3959296-A | CARDIOVASCULAR AGENTS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-05-25 | — | — | US | disclosed |