Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 8/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.40 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7799400 | 0.85 | MAPT (0.55) | ERN1ALDH1A1HPGDKDM4EMEN1 | |
| SCHEMBL4321242 | 0.85 | ERN1 (0.50) | ERN1ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL3997757 | 0.83 | ALDH1A1 (0.60) | ERN1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL6021915 | 0.81 | PTGDR2 (0.61) | ERN1ALDH1A1KDM4ETSHRMEN1 | |
| SCHEMBL11783380 | 0.80 | PTGDR2 (0.64) | ALDH1A1HPGDKDM4ETSHRHSD17B10 | |
| SCHEMBL2556381 | 0.80 | SMN1; SMN2 (0.50) | ERN1ALDH1A1HPGDKDM4EMEN1 | |
| SCHEMBL15330091 | 0.80 | ERN1 (0.51) | ERN1ALDH1A1MEN1KMT2APTGDR2 | |
| SCHEMBL15331190 | 0.79 | ERN1 (0.50) | ERN1ALDH1A1HPGDKMT2APTGDR2 | |
| SCHEMBL2556439 | 0.79 | ERN1 (0.50) | ERN1ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL2552640 | 0.77 | MAPT (0.48) | ERN1ALDH1A1HPGDKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3968117-A | CARDIOVASCULAR | BAYER AKTIENGESELLSCHAFT (DT) | 1976-07-06 | — | — | US | disclosed |
| US-3959296-A | CARDIOVASCULAR AGENTS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-05-25 | — | — | US | disclosed |