SCHEMBL11784259

SCHEMBL11784259

C=Cc1ccc2c(c1)c1ccccc1n2C(C)C

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.52
MEN1 O00255 1/20 0.52
NPY5R Q15761 4/20 0.46
BCHE P06276 1/20 0.43
ACHE P22303 1/20 0.43
KDM4E B2RXH2 4/20 0.41
HTT P42858 3/20 0.41
POLB P06746 2/20 0.41
PKM P14618 1/20 0.41
SRC P12931 2/20 0.40
PTGER4 P35408 1/20 0.40
MAPT P10636 3/20 0.40
TSHR P16473 2/20 0.40
CASP1 P29466 2/20 0.40
MAPK1 P28482 1/20 0.40
CASP7 P55210 1/20 0.40
ATM Q13315 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
RORC P51449 2/20 0.39
ALDH1A1 P00352 4/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4728764 0.84 MEN1 (0.56) KMT2AMEN1NPY5RBCHEACHE
SCHEMBL5670066 0.81 GPR3 (0.57) KMT2AMEN1KDM4EHTTPOLB
SCHEMBL18056716 0.81 MEN1 (0.35) KMT2AMEN1NPY5RKDM4E
SCHEMBL29780042 0.78 BCHE (0.59) KMT2AMEN1NPY5RBCHEACHE
SCHEMBL150044 0.78 BCHE (0.59) KMT2AMEN1NPY5RBCHEACHE
SCHEMBL16218437 0.78 SRC (0.42) KMT2AMEN1KDM4EHTTPOLB
SCHEMBL26237871 0.78 MEN1 (0.59) KMT2AMEN1NPY5RBCHEACHE
SCHEMBL766095 0.77 KDM4E (0.67) KMT2AMEN1BCHEACHEKDM4E
SCHEMBL31454256 0.77 KDM4E (0.67) KMT2AMEN1BCHEACHEKDM4E
SCHEMBL4897630 0.77 KDM4E (0.48) KMT2AMEN1KDM4EHTTPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4060426-A Tin indium oxide and polyvinylcarbazole layered polarized photovoltaic cell POLAROID CORPORATION (US) 1977-11-29 US disclosed