Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1759721 | 0.92 | TDP1 (0.46) | MAPK1TDP1HSD17B10 | |
| SCHEMBL482801 | 0.78 | MAPK1 (0.48) | MAPK1TDP1HSD17B10LMNA | |
| SCHEMBL6129172 | 0.74 | TDP1 (0.41) | MAPK1TDP1HSD17B10 | |
| SCHEMBL2703 | 0.68 | — | — | |
| SCHEMBL8149144 | 0.68 | TDP1 (0.46) | MAPK1TDP1HSD17B10LMNA | |
| SCHEMBL9910554 | 0.68 | TDP1 (0.46) | MAPK1TDP1HSD17B10LMNA | |
| SCHEMBL28456948 | 0.68 | — | — | |
| SCHEMBL1416868 | 0.68 | — | — | |
| SCHEMBL1416856 | 0.68 | — | — | |
| SCHEMBL9264164 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3996269-A | USEFUL AS TEXTILE TREATING AGENTS, FROM GLYCOL AMINES AND UREA | ICI UNITED STATES INC. (US) | 1976-12-07 | — | — | US | disclosed |
| US-3981913-A | TEXTILE TREATING AGENTS, CHEMICAL INTERMEDIATES | ICI UNITED STATES INC. (US) | 1976-09-21 | — | — | US | disclosed |
| US-3965072-A | Polyurea-urethane polymers from urea, diamines and aminoalcohols | ICI UNITED STATES INC. (US) | 1976-06-22 | — | — | US | disclosed |