Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL482801 | 0.76 | MAPK1 (0.48) | TDP1MAPK1HSD17B10TSHR | |
| SCHEMBL11786191 | 0.74 | MAPK1 (0.41) | TDP1MAPK1HSD17B10 | |
| SCHEMBL28025487 | 0.68 | TDP1 (0.46) | TDP1MAPK1HSD17B10 | |
| SCHEMBL1759721 | 0.68 | TDP1 (0.46) | TDP1MAPK1HSD17B10 | |
| SCHEMBL21154123 | 0.67 | MAPK1 (0.48) | TDP1MAPK1 | |
| SCHEMBL9910554 | 0.66 | TDP1 (0.46) | TDP1MAPK1HSD17B10TSHR | |
| SCHEMBL975267 | 0.66 | — | — | |
| SCHEMBL2703 | 0.66 | — | — | |
| SCHEMBL1416856 | 0.66 | — | — | |
| SCHEMBL28456948 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1607424-A1 | A method of direct-to-metal coating | Bayer MaterialScience LLC (US) | 2005-12-21 | — | — | EP | claimed |
| US-20050277732-A1 | Two-component coating composition | COVESTRO LLC | 2005-12-15 | — | — | US | claimed |
| CN-1721485-A | Polyurethane dispersion prepared from a high acid functional polyester | BAYER MATERIALSCIENCE LLC (US) | 2006-01-18 | — | — | CN | disclosed |
| US-20050288431-A1 | Polyurethane dispersion prepared from a high acid functional polyester | BAYER MATERIALSCIENCE LLC | 2005-12-29 | — | — | US | disclosed |
| US-20050288430-A1 | Polyurethane dispersions with high acid content | BAYER POLYMERS LLC | 2005-12-29 | — | — | US | disclosed |
| EP-1609809-A1 | Polyurethane dispersions with high acid content | Bayer MaterialScience LLC (US) | 2005-12-28 | — | — | EP | disclosed |
| EP-1609808-A2 | Polyurethane dispersion prepared from a high acid functional polyester | Bayer MaterialScience LLC (US) | 2005-12-28 | — | — | EP | disclosed |
| CN-1712423-A | Polyurethane dispersions with high acid content | BAYER MATERIALSCIENCE LLC (US) | 2005-12-28 | — | — | CN | disclosed |
| EP-1607424-A1 | A method of direct-to-metal coating | Bayer MaterialScience LLC (US) | 2005-12-21 | — | — | EP | disclosed |
| US-20050277732-A1 | Two-component coating composition | COVESTRO LLC | 2005-12-15 | — | — | US | disclosed |