SCHEMBL11787397

SCHEMBL11787397

Cc1cc(C)c(-c2nc(-c3cc(C(C)(C)C)c(O)c(C(C)(C)C)c3)[nH]c2-c2ccccc2)c(C)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMPD3 Q9NY59 5/20 0.49
NOX1 Q9Y5S8 2/20 0.49
TP53 P04637 1/20 0.44
MAPT P10636 1/20 0.44
PTPN1 P18031 1/20 0.43
KDM4E B2RXH2 2/20 0.43
MEN1 O00255 2/20 0.43
ALDH1A1 P00352 2/20 0.43
KMT2A Q03164 2/20 0.43
GLA P06280 1/20 0.43
GAA P10253 1/20 0.43
HPGD P15428 1/20 0.43
CYP1A2 P05177 1/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2C19 P33261 1/20 0.43
MAPK14 Q16539 2/20 0.41
MAPK13 O15264 1/20 0.41
RAF1 P04049 1/20 0.41
BRAF P15056 1/20 0.41
MAPK12 P53778 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5151007 0.86 SMPD3 (0.64) SMPD3NOX1TP53MAPTPTPN1
Hydrochloric Acid SCHEMBL10787659 0.85 SMPD3 (0.62) SMPD3NOX1TP53MAPTPTPN1
SCHEMBL12958658 0.81 SMPD3 (0.47) SMPD3NOX1TP53MAPTPTPN1
SCHEMBL6468933 0.81 MAPK13 (0.64) SMPD3NOX1MAPK14MAPK13RAF1
SCHEMBL11596759 0.78 NOX1 (0.69) SMPD3NOX1TP53MAPTPTPN1
SCHEMBL11596752 0.77 SMPD3 (0.47) SMPD3NOX1TP53MAPTPTPN1
SCHEMBL10791892 0.76 SMPD3 (0.56) SMPD3NOX1MAPT
SCHEMBL5623031 0.76 KDM4E (0.57) SMPD3NOX1MAPTPTPN1KDM4E
SCHEMBL12152244 0.74 NOX1 (0.68) SMPD3NOX1TP53MAPTPTPN1
SCHEMBL14003089 0.72 NOX1 (0.60) SMPD3NOX1TP53MAPTPTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3985565-A Photothermographic, composition using a phenolic leuco dye as a reducing agent EASTMAN KODAK COMPANY (US) 1976-10-12 US disclosed