SCHEMBL12152244

SCHEMBL12152244

Cc1cc(-c2nc(-c3ccccc3)c(-c3ccccc3)[nH]2)cc(C)c1O

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOX1 Q9Y5S8 3/20 0.68
SMPD3 Q9NY59 2/20 0.68
ALOX5 P09917 1/20 0.66
PTPN1 P18031 1/20 0.61
TP53 P04637 4/20 0.60
MAPT P10636 4/20 0.60
MGAM O43451 1/20 0.57
MAPK13 O15264 4/20 0.56
MAPK12 P53778 4/20 0.56
MAPK11 Q15759 4/20 0.56
MAPK14 Q16539 4/20 0.56
RAF1 P04049 2/20 0.56
MAPK9 P45984 1/20 0.56
KDM4E B2RXH2 2/20 0.56
MEN1 O00255 2/20 0.56
ALDH1A1 P00352 2/20 0.56
KMT2A Q03164 2/20 0.56
GCGR P47871 2/20 0.56
CYP1A2 P05177 1/20 0.56
CYP3A4 P08684 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6466313 0.93 ALOX5 (0.77) NOX1SMPD3ALOX5MAPK13MAPK12
SCHEMBL12152165 0.88 ALOX5 (0.70) NOX1SMPD3ALOX5PTPN1TP53
SCHEMBL12103632 0.88 SMPD3 (0.71) NOX1SMPD3ALOX5PTPN1TP53
SCHEMBL12152166 0.85 ALOX5 (0.66) NOX1SMPD3ALOX5PTPN1TP53
SCHEMBL6469493 0.85 ALOX5 (0.67) NOX1SMPD3ALOX5PTPN1TP53
SCHEMBL12311036 0.85 KDM4E (0.67) NOX1SMPD3ALOX5PTPN1TP53
SCHEMBL12103631 0.83 NOX1 (0.64) NOX1SMPD3ALOX5PTPN1TP53
SCHEMBL11595659 0.83 SMPD3 (0.76) NOX1SMPD3ALOX5TP53MAPT
SCHEMBL6468085 0.82 ALOX5 (0.69) NOX1SMPD3ALOX5MAPK13MAPK12
SCHEMBL8030085 0.82 NOX1 (0.64) NOX1SMPD3PTPN1TP53MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8999430-B2 Method of manufacturing display element KONICA MINOLTA HOLDINGS, INC. (JP) 2015-04-07 US disclosed
US-8586270-B2 Electrophotographic photoconductor, electrophotographic method, and electrophotographic apparatus RICOH COMPANY, LTD. (JP) 2013-11-19 US disclosed
US-8384982-B2 Display element KONICA MINOLTA HOLDINGS, INC. (JP) 2013-02-26 US disclosed
US-20120251934-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, ELECTROPHOTOGRAPHIC METHOD, AND ELECTROPHOTOGRAPHIC APPARATUS RICOH COMPANY, LTD. (JP) 2012-10-04 US disclosed
US-20120251934-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, ELECTROPHOTOGRAPHIC METHOD, AND ELECTROPHOTOGRAPHIC APPARATUS RICOH COMPANY, LTD. (JP) 2012-10-04 US disclosed
US-8049948-B2 Process for producing electrochemical display element and electrochemical display element KONICA MINOLTA HOLDINGS, INC. (JP) 2011-11-01 US disclosed
US-8014056-B2 Display element and method of driving the same KONICA MINOLTA HOLDINGS, INC. (JP) 2011-09-06 US disclosed
US-8004742-B2 Electrochromic display device KONICA MINOLTA HOLDINGS, INC. (JP) 2011-08-23 US disclosed
US-20110058244-A1 ELECTROCHROMIC DISPLAY ELEMENT KONICA MINOLTA HOLDINGS, INC. (JP) 2011-03-10 US disclosed
US-20100213813-A1 DISPLAY ELEMENT EDISON INNOVATIONS LLC 2010-08-26 US disclosed
US-20100166946-A1 METHOD OF MANUFACTURING DISPLAY ELEMENT KONICA MINOLTA HOLDINGS, INC. (JP) 2010-07-01 US disclosed
US-20100134864-A1 PROCESS FOR PRODUCING ELECTROCHEMICAL DISPLAY ELEMENT AND ELECTROCHEMICAL DISPLAY ELEMENT KONICA MINOLTA HOLDINGS ,INC. (JP) 2010-06-03 US disclosed
US-20100091353-A1 DISPLAY ELEMENT AND METHOD OF DRIVING THE SAME KONICA MINOLTA HOLDINGS, INC. (JP) 2010-04-15 US disclosed
US-20090316249-A1 ELECTROCHROMIC DISPLAY DEVICE KONICA MINOLTA HOLDINGS, INC. (JP) 2009-12-24 US disclosed
US-7619803-B2 Electrochromic display element and full-color electrochromic display element KONICA MINOLTA HOLDINGS, INC. (JP) 2009-11-17 US disclosed
US-20090027757-A1 ELECTROCHROMIC DISPLAY ELEMENT AND FULL-COLOR ELECTROCHROMIC DISPLAY ELEMENT KONICA MINOLTA HOLDINGS, INC. (JP) 2009-01-29 US disclosed