Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN2A | Q99250 | 2/20 | 0.61 |
| ▸ | HPN | P05981 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.40 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11790251 | 0.90 | SCN2A (0.62) | SCN2AHPNTDP1MEN1KMT2A | |
| SCHEMBL11791794 | 0.79 | ALDH1A1 (0.55) | MEN1KMT2ACA12CA2CA9 | |
| SCHEMBL11792049 | 0.78 | HTT (0.43) | MEN1KMT2ARECQLCYP2C19TSHR | |
| SCHEMBL11791994 | 0.78 | NOTUM (0.38) | TDP1CA1CA2CA9POLB | |
| SCHEMBL11669113 | 0.77 | SCN2A (1.00) | SCN2AHPNTDP1MEN1KMT2A | |
| SCHEMBL30758587 | 0.77 | SCN2A (1.00) | SCN2AHPNTDP1MEN1KMT2A | |
| SCHEMBL11787924 | 0.75 | SCN2A (0.41) | SCN2AMEN1KMT2ACA12CA1 | |
| SCHEMBL11792757 | 0.75 | BRD4 (0.39) | MEN1KMT2AL3MBTL1CYP1A2CYP3A4 | |
| SCHEMBL11787157 | 0.75 | CA1 (0.37) | SCN2AMEN1KMT2ACA12CA1 | |
| SCHEMBL11794014 | 0.74 | SCN2A (0.40) | SCN2AMEN1KMT2ACA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3998954-A | 1,3(2H,4H)-Dioxoisoquinoline-4-carboxamides used as anti-inflammatory agents | PFIZER INC. (US) | 1976-12-21 | — | — | US | disclosed |