SCHEMBL11788015

SCHEMBL11788015

COc1cc([N+](=O)[O-])cc2c1OC1(C=C2)N(C)c2ccc([N+](=O)[O-])cc2C1(C)C

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.57
MEN1 O00255 3/20 0.57
GFER P55789 1/20 0.57
HTT P42858 3/20 0.39
LMNA P02545 8/20 0.39
MAPT P10636 6/20 0.39
GAA P10253 3/20 0.39
TDP1 Q9NUW8 3/20 0.39
NPSR1 Q6W5P4 2/20 0.39
RECQL P46063 2/20 0.39
ALPG P10696 1/20 0.39
TP53 P04637 1/20 0.39
ALOX15 P16050 1/20 0.39
HSD17B10 Q99714 1/20 0.39
TLR3 O15455 1/20 0.36
SMN1; SMN2 Q16637 5/20 0.35
ALDH1A1 P00352 4/20 0.35
MAPK1 P28482 3/20 0.35
SNCA P37840 1/20 0.35
PKM P14618 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30612721 1.00 KMT2A (0.57) KMT2AMEN1GFERHTTLMNA
SCHEMBL8680176 0.92 KMT2A (0.48) KMT2AMEN1GFERHTTLMNA
SCHEMBL8680217 0.92 MEN1 (0.48) KMT2AMEN1GFERHTTLMNA
SCHEMBL8682710 0.91 MEN1 (0.48) KMT2AMEN1GFERHTTLMNA
SCHEMBL6140171 0.91 MEN1 (0.48) KMT2AMEN1GFERHTTLMNA
SCHEMBL30612733 0.91 MEN1 (0.48) KMT2AMEN1GFERHTTLMNA
SCHEMBL6139989 0.91 MEN1 (0.48) KMT2AMEN1GFERHTTLMNA
SCHEMBL8680196 0.91 KMT2A (0.48) KMT2AMEN1GFERHTTLMNA
SCHEMBL30612732 0.90 MAPT (0.50) KMT2AMEN1GFERHTTLMNA
SCHEMBL13326515 0.90 MAPT (0.50) KMT2AMEN1GFERHTTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230323595-A1 WATER-SOLUBLE FILM BASED DELIVERY SYSTEMS FOR COLORANTS, GLITTER, AND OTHER CHEMISTRIES CRAYOLA LLC (US) 2023-10-12 US disclosed
US-20230323051-A1 WATER-SOLUBLE FILM BASED DELIVERY SYSTEMS FOR COLORANTS, GLITTER, AND OTHER ARTISTIC EFFECTS CRAYOLA LLC (US) 2023-10-12 US disclosed
US-11746235-B2 Two part silicone moldable eraser CRAYOLA LLC (US) 2023-09-05 US disclosed
US-11007813-B2 Integrated highlighting and shading marker system CRAYOLA LLC (US) 2021-05-18 US disclosed
US-20200399472-A1 TWO PART SILICONE MOLDABLE ERASER CRAYOLA LLC (US) 2020-12-24 US disclosed
US-3933509-A Photo-polymerizable composition containing an acid salt of an indolinobenzospiropyran FUJI PHOTO FILM CO., LTD. (JA) 1976-01-20 US disclosed