SCHEMBL6140171

SCHEMBL6140171

COc1cc([N+](=O)[O-])cc2c1OC1(C=C2)N(C)c2ccc(Cl)cc2C1(C)C

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.48
KMT2A Q03164 4/20 0.48
GFER P55789 1/20 0.48
MAPT P10636 5/20 0.37
LMNA P02545 4/20 0.37
GAA P10253 3/20 0.37
NPSR1 Q6W5P4 2/20 0.37
RECQL P46063 2/20 0.37
TDP1 Q9NUW8 2/20 0.37
ALPG P10696 1/20 0.37
TP53 P04637 1/20 0.37
ALOX15 P16050 1/20 0.37
HSD17B10 Q99714 1/20 0.37
SMN1; SMN2 Q16637 5/20 0.34
MAPK1 P28482 4/20 0.34
ALDH1A1 P00352 3/20 0.34
KCNMA1 Q12791 1/20 0.33
HTT P42858 2/20 0.32
TLR3 O15455 1/20 0.32
PLIN1 O60240 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30612733 1.00 MEN1 (0.48) MEN1KMT2AGFERMAPTLMNA
SCHEMBL30612721 0.91 KMT2A (0.57) MEN1KMT2AGFERMAPTLMNA
SCHEMBL11788015 0.91 KMT2A (0.57) MEN1KMT2AGFERMAPTLMNA
SCHEMBL8684749 0.90 KMT2A (0.46) MEN1KMT2AGFERMAPTLMNA
SCHEMBL8680217 0.89 MEN1 (0.48) MEN1KMT2AGFERMAPTLMNA
SCHEMBL8680176 0.89 KMT2A (0.48) MEN1KMT2AGFERMAPTLMNA
SCHEMBL8682710 0.89 MEN1 (0.48) MEN1KMT2AGFERMAPTLMNA
SCHEMBL6139989 0.89 MEN1 (0.48) MEN1KMT2AGFERMAPTLMNA
SCHEMBL8680196 0.89 KMT2A (0.48) MEN1KMT2AGFERMAPTLMNA
SCHEMBL8680224 0.88 MEN1 (0.51) MEN1KMT2AGFERMAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5759729-A A DRY TONER COMPRISING A RESIN, PHOTOCHROMATIC SPIROPYRAN, -OXAZINE OR -THIOPYRAN DYE AND A CHARGE CONTROL AGENT;ELECTROGRAPHY; XEROGRAPHY XEROX CORPORATION (US) 1998-06-02 US claimed
US-20230323595-A1 WATER-SOLUBLE FILM BASED DELIVERY SYSTEMS FOR COLORANTS, GLITTER, AND OTHER CHEMISTRIES CRAYOLA LLC (US) 2023-10-12 US disclosed
US-20230323051-A1 WATER-SOLUBLE FILM BASED DELIVERY SYSTEMS FOR COLORANTS, GLITTER, AND OTHER ARTISTIC EFFECTS CRAYOLA LLC (US) 2023-10-12 US disclosed
US-11746235-B2 Two part silicone moldable eraser CRAYOLA LLC (US) 2023-09-05 US disclosed
US-20200399472-A1 TWO PART SILICONE MOLDABLE ERASER CRAYOLA LLC (US) 2020-12-24 US disclosed
US-20050019954-A1 Photochromic dyes for microsphere based sensor EASTMAN KODAK COMPANY 2005-01-27 US disclosed
US-5759729-A A DRY TONER COMPRISING A RESIN, PHOTOCHROMATIC SPIROPYRAN, -OXAZINE OR -THIOPYRAN DYE AND A CHARGE CONTROL AGENT;ELECTROGRAPHY; XEROGRAPHY XEROX CORPORATION (US) 1998-06-02 US disclosed
US-5710420-A Method for embedding and recovering machine-readable information XEROX CORPORATION (US) 1998-01-20 US disclosed
US-5593486-A Photochromic hot melt ink compositions XEROX CORPORATION (US) 1997-01-14 US disclosed
US-5551973-A LIQUID CRYSTAL GEL PHASE, MICROEMULSION PHASE XEROX CORPORATION (US) 1996-09-03 US disclosed
EP-0230941-B1 PHOTOPOLYMERISABLE COMPOSITION AND PHOTOPOLYMERISABLE REGISTRATION MATERIAL CONTAINING IT HOECHST AKTIENGESELLSCHAFT (DE) 1992-09-09 EP disclosed
EP-0363776-A2 Light-sensitive composition and light-sensitive copy material produced therewith HOECHST AKTIENGESELLSCHAFT (DE) 1990-04-18 EP disclosed
US-4780393-A POLYMERIC BINDER, TERMINAL ETHYLENIC COMPOUND, PHOTOINITIATOR, LEVCO BASE OF TRIARYLMETHANE DYE AND PHOTOC ROMIC SPIRO-INDOLINO-BENZOPYRAN COMPOUND HOECHST AKTIENGESELLSCHAFT (DE) 1988-10-25 US disclosed
EP-0230941-A2 Photopolymerisable composition and photopolymerisable registration material containing it HOECHST AKTIENGESELLSCHAFT (DE) 1987-08-05 EP disclosed