Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.43 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 3/20 | 0.37 |
| ▸ | CES1 | P23141 | 3/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.35 |
| ▸ | PPARG | P37231 | 7/20 | 0.35 |
| ▸ | PPARD | Q03181 | 7/20 | 0.35 |
| ▸ | PPARA | Q07869 | 7/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.35 |
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11785813 | 0.98 | SPHK2 (0.40) | SPHK2SPHK1MEN1KMT2AFAAH | |
| SCHEMBL25793038 | 0.81 | SPHK2 (0.46) | SPHK2SPHK1MEN1KMT2AFAAH | |
| SCHEMBL30739170 | 0.81 | SPHK2 (0.46) | SPHK2SPHK1MEN1KMT2AFAAH | |
| SCHEMBL29658119 | 0.81 | SPHK2 (0.46) | SPHK2SPHK1MEN1KMT2AFAAH | |
| SCHEMBL28018511 | 0.78 | CES2 (0.48) | SPHK2SPHK1MEN1KMT2AFAAH | |
| SCHEMBL8350143 | 0.72 | SPHK2 (0.52) | SPHK2SPHK1MEN1KMT2AFAAH | |
| SCHEMBL12356543 | 0.71 | CES2 (0.48) | SPHK2SPHK1MEN1KMT2ACES2 | |
| SCHEMBL12437784 | 0.71 | — | — | |
| SCHEMBL14730398 | 0.71 | SPHK2 (0.38) | SPHK2SPHK1MEN1KMT2AFAAH | |
| SCHEMBL14767459 | 0.69 | CES2 (0.48) | MEN1KMT2AFAAHCES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4044118-A | N-1-HALOMETHYL-1-S-DIALKYLPHOSPHOROTHIOATE METHINYL PHTHALIMIDE ON | TEXACO INC. (US) | 1977-08-23 | — | — | US | disclosed |
| US-3939272-A | 5,6-DIHYDRO-2-METHYL-1,4-OXATHIIN-3-CARBOXYANILIDE-4,4-DIOXIDE, ALKYLATED PHENOL | TEXACO INC. (US) | 1976-02-17 | — | — | US | disclosed |