Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CCR3 | P51677 | 1/20 | 0.42 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18640269 | 0.84 | KCNH2 (0.51) | KCNH2KMT2ACCR3SPHK1 | |
| SCHEMBL18640221 | 0.83 | KCNH2 (0.53) | KCNH2KMT2ASPHK1 | |
| SCHEMBL11404739 | 0.81 | KCNH2 (0.56) | KCNH2SPHK1 | |
| SCHEMBL18640359 | 0.80 | KCNH2 (0.46) | KCNH2CCR3 | |
| SCHEMBL10589721 | 0.79 | KCNH2 (0.49) | KCNH2 | |
| SCHEMBL11729674 | 0.79 | CA1 (0.41) | CCR3 | |
| SCHEMBL28101802 | 0.78 | KCNH2 (0.57) | KCNH2KMT2ASPHK1 | |
| SCHEMBL11498959 | 0.78 | KCNH2 (0.53) | KCNH2 | |
| SCHEMBL25689644 | 0.77 | GAA (0.53) | CCR3SPHK1 | |
| SCHEMBL18557917 | 0.76 | GBA1 (0.55) | SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4012392-A | ANALGESICS, MORPHINE ANTAGONISTS | ACF CHEMIEFARMA N.V. (NL) | 1977-03-15 | — | — | US | disclosed |