Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | GABRA1 | P14867 | 5/20 | 0.56 |
| ▸ | GABRG2 | P18507 | 5/20 | 0.56 |
| ▸ | GABRB3 | P28472 | 5/20 | 0.56 |
| ▸ | GABRA3 | P34903 | 5/20 | 0.56 |
| ▸ | GABRA2 | P47869 | 5/20 | 0.56 |
| ▸ | GABRB2 | P47870 | 5/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.49 |
| ▸ | GABRP | O00591 | 1/20 | 0.49 |
| ▸ | GABRD | O14764 | 1/20 | 0.49 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.49 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.49 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11786507 | 0.91 | POLB (0.68) | POLBLMNAKDM4EALDH1A1GABRA1 | |
| SCHEMBL11739805 | 0.84 | POLB (0.60) | POLBLMNAKDM4EALDH1A1GABRA1 | |
| SCHEMBL11314928 | 0.83 | KMT2A (0.50) | POLBLMNAKDM4EALDH1A1RAB9A | |
| SCHEMBL11784754 | 0.78 | AVPR1A (0.67) | POLBLMNAKDM4EALDH1A1GABRA1 | |
| SCHEMBL13116826 | 0.78 | POLB (0.67) | POLBLMNAKDM4EALDH1A1GABRA1 | |
| SCHEMBL3849918 | 0.78 | POLB (1.00) | POLBLMNAKDM4EALDH1A1GABRA1 | |
| SCHEMBL11732042 | 0.77 | GABRA1 (0.56) | POLBLMNAKDM4EALDH1A1GABRA1 | |
| SCHEMBL30515255 | 0.77 | POLB (0.66) | POLBLMNAKDM4EALDH1A1GABRA1 | |
| SCHEMBL11767169 | 0.77 | POLB (0.66) | POLBLMNAKDM4EALDH1A1GABRA1 | |
| SCHEMBL11738779 | 0.77 | POLB (0.65) | POLBLMNAKDM4EALDH1A1GABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE28973-E | PARKINSON'S DISEASE | A. H. ROBINS COMPANY, INCORPORATED (US) | 1976-09-21 | — | — | US | disclosed |