Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.69 |
| ▸ | MAPT | P10636 | 6/20 | 0.69 |
| ▸ | MEN1 | O00255 | 5/20 | 0.69 |
| ▸ | NPC1 | O15118 | 4/20 | 0.69 |
| ▸ | RAB9A | P51151 | 3/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.69 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.56 |
| ▸ | RELA | Q04206 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | CCR6 | P51684 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.50 |
| ▸ | PPIA | P62937 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3604286 | 0.89 | KMT2A (0.74) | KMT2AMAPTMEN1NPC1RAB9A | |
| SCHEMBL26742261 | 0.84 | HTT (0.56) | KMT2AMAPTMEN1NPC1RAB9A | |
| SCHEMBL5250932 | 0.83 | MEN1 (0.80) | KMT2AMAPTMEN1NPC1RAB9A | |
| SCHEMBL11763360 | 0.82 | SMN1; SMN2 (0.57) | KMT2AMAPTMEN1NPC1ALDH1A1 | |
| SCHEMBL11788000 | 0.82 | KMT2A (0.74) | KMT2AMAPTMEN1NPC1RAB9A | |
| SCHEMBL5249571 | 0.82 | MAPT (1.00) | KMT2AMAPTMEN1NPC1RAB9A | |
| SCHEMBL5250046 | 0.82 | MEN1 (0.78) | KMT2AMAPTMEN1NPC1RAB9A | |
| SCHEMBL30892309 | 0.81 | SYK (0.54) | KMT2AMAPTMEN1NPC1RAB9A | |
| SCHEMBL29218438 | 0.81 | SYK (0.54) | KMT2AMAPTMEN1NPC1RAB9A | |
| SCHEMBL11833609 | 0.81 | HTT (0.68) | KMT2AMAPTMEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3984415-A | ANTIINFLAMMATORY, ANTI-ULCERATIVE, ANALGETIC, ANTIPYRETIC, ANTIHISTAMINIC AND CNS DEPRESSANTS | HISAMITSU PHARMACEUTICAL CO., INC. (JA) | 1976-10-05 | — | — | US | disclosed |