Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 9/20 | 0.74 |
| ▸ | MEN1 | O00255 | 8/20 | 0.74 |
| ▸ | MAPT | P10636 | 7/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.74 |
| ▸ | NPC1 | O15118 | 2/20 | 0.74 |
| ▸ | RAB9A | P51151 | 2/20 | 0.74 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.74 |
| ▸ | POLB | P06746 | 4/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | BAZ1A | Q9NRL2 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.47 |
| ▸ | DDX3X | O00571 | 1/20 | 0.47 |
| ▸ | PPIA | P62937 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5250932 | 0.86 | MEN1 (0.80) | KMT2AMEN1MAPTALDH1A1NPC1 | |
| SCHEMBL3604286 | 0.86 | KMT2A (0.74) | KMT2AMEN1MAPTALDH1A1NPC1 | |
| SCHEMBL5250046 | 0.85 | MEN1 (0.78) | KMT2AMEN1MAPTALDH1A1NPC1 | |
| SCHEMBL5249571 | 0.85 | MAPT (1.00) | KMT2AMEN1MAPTALDH1A1NPC1 | |
| SCHEMBL22492830 | 0.85 | MAPT (0.73) | KMT2AMEN1MAPTALDH1A1NPC1 | |
| SCHEMBL22492743 | 0.84 | MEN1 (0.71) | KMT2AMEN1MAPTALDH1A1NPC1 | |
| SCHEMBL11802310 | 0.82 | MAPT (0.66) | KMT2AMEN1MAPTALDH1A1NPC1 | |
| SCHEMBL11790155 | 0.82 | KMT2A (0.69) | KMT2AMEN1MAPTALDH1A1NPC1 | |
| SCHEMBL11762199 | 0.80 | AKR1C3 (0.58) | KMT2AMEN1MAPTALDH1A1NPC1 | |
| SCHEMBL21069538 | 0.77 | ALDH1A1 (0.65) | KMT2AMEN1MAPTALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3984415-A | ANTIINFLAMMATORY, ANTI-ULCERATIVE, ANALGETIC, ANTIPYRETIC, ANTIHISTAMINIC AND CNS DEPRESSANTS | HISAMITSU PHARMACEUTICAL CO., INC. (JA) | 1976-10-05 | — | — | US | disclosed |