Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 5/20 | 0.60 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.60 |
| ▸ | PGR | P06401 | 4/20 | 0.60 |
| ▸ | HRH1 | P35367 | 1/20 | 0.60 |
| ▸ | FNTA | P49354 | 5/20 | 0.53 |
| ▸ | FNTB | P49356 | 5/20 | 0.53 |
| ▸ | AR | P10275 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | SHBG | P04278 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11790607 | 1.00 | HIF1A (0.60) | HIF1ANR3C1PGRHRH1FNTA | |
| SCHEMBL11789084 | 0.85 | HIF1A (0.48) | HIF1ANR3C1PGRHRH1FNTA | |
| SCHEMBL11789075 | 0.85 | HIF1A (0.48) | HIF1ANR3C1PGRHRH1FNTA | |
| SCHEMBL11791044 | 0.85 | HIF1A (0.72) | HIF1ANR3C1PGRHRH1FNTA | |
| SCHEMBL11790647 | 0.85 | HIF1A (0.72) | HIF1ANR3C1PGRHRH1FNTA | |
| SCHEMBL11791040 | 0.85 | HIF1A (0.72) | HIF1ANR3C1PGRHRH1FNTA | |
| SCHEMBL4738 | 0.84 | NR3C1 (0.76) | HIF1ANR3C1PGRHRH1FNTA | |
| SCHEMBL11788258 | 0.83 | NR3C1 (0.51) | HIF1ANR3C1PGRHRH1FNTA | |
| SCHEMBL11788265 | 0.83 | NR3C1 (0.51) | HIF1ANR3C1PGRHRH1FNTA | |
| SCHEMBL11789152 | 0.79 | HIF1A (0.58) | HIF1ANR3C1PGRHRH1FNTA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3931167-A | Process for the manufacture of 3-keto-6-azido-4,6-bis-dehydro-steroids and intermediates useful therein | SCHERING CORPORATION (US) | 1976-01-06 | — | — | US | disclosed |