Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ICAM1 | P05362 | 1/20 | 0.38 |
| ▸ | SELE | P16581 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.36 |
| ▸ | CHRNG | P07510 | 1/20 | 0.36 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | CHRND | Q07001 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11883764 | 0.99 | ICAM1 (0.37) | ICAM1SELEDRD2DRD1SLC6A2 | |
| Bromomethane SCHEMBL11883047 | 0.99 | ICAM1 (0.37) | ICAM1SELEDRD2DRD1SLC6A2 | |
| Bromomethane SCHEMBL11883325 | 0.88 | NPSR1 (0.38) | ICAM1SELEDRD2DRD1SLC6A3 | |
| SCHEMBL11876435 | 0.88 | HSD17B10 (0.39) | ICAM1SELEDRD2DRD1SLC6A3 | |
| Hydrochloric Acid SCHEMBL11877908 | 0.87 | NPSR1 (0.38) | ICAM1SELEDRD2DRD1SLC6A3 | |
| Bromomethane SCHEMBL11879094 | 0.85 | LMNA (0.44) | SLC6A2SLC6A3CHRNB4CHRNA3SMN1; SMN2 | |
| SCHEMBL11883619 | 0.84 | LMNA (0.45) | SLC6A2SLC6A3CHRNB4CHRNA3SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11794874 | 0.84 | SMN1; SMN2 (0.44) | SLC6A2SLC6A3CHRNB4CHRNA3SMN1; SMN2 | |
| SCHEMBL11794862 | 0.82 | GLA (0.53) | SMN1; SMN2POLBNPSR1HSD17B10MAPT | |
| SCHEMBL11881855 | 0.81 | RXFP1 (0.39) | SMN1; SMN2CA12CA9POLBNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3954748-A | ANTIEMETICS | SOCIETE D'ETUDES SCIENTIFIQUES ET INDUSTRIELLES DE L'ILE-DE-FRANCE (FR) | 1976-05-04 | — | — | US | claimed |
| US-3976780-A | Methods of protection against emesis in mammals by administration of a 3-alkoxy-thianaphthene-2-carboxamide | SOCIETE D'ETUDES SCIENTIFIQUES ET INDUSTRIELLES L'ILE-DE-FRANCE (FR) | 1976-08-24 | — | — | US | disclosed |
| US-3954748-A | ANTIEMETICS | SOCIETE D'ETUDES SCIENTIFIQUES ET INDUSTRIELLES DE L'ILE-DE-FRANCE (FR) | 1976-05-04 | — | — | US | disclosed |