SCHEMBL11794883

SCHEMBL11794883

CSc1c(O)cc(C)oc1=O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 10/20 0.44
KMT2A Q03164 10/20 0.44
ANTXR2 P58335 1/20 0.44
PKM P14618 1/20 0.44
RAB9A P51151 1/20 0.44
MAOA P21397 1/20 0.43
GLA P06280 1/20 0.41
CYP3A4 P08684 1/20 0.41
L3MBTL1 Q9Y468 4/20 0.41
ELANE P08246 2/20 0.41
MAPT P10636 6/20 0.40
ALDH1A1 P00352 5/20 0.40
KDM4E B2RXH2 3/20 0.40
RECQL P46063 2/20 0.40
TDP1 Q9NUW8 1/20 0.40
MCL1 Q07820 1/20 0.40
POLB P06746 1/20 0.39
NQO1 P15559 1/20 0.38
GAA P10253 3/20 0.38
ALOX12 P18054 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11791101 0.86 ANTXR2 (0.46) MEN1KMT2AANTXR2PKMRAB9A
SCHEMBL11789287 0.79 ANTXR2 (0.41) MEN1KMT2AANTXR2PKMRAB9A
SCHEMBL11796654 0.79 ELANE (0.44) MEN1KMT2AANTXR2PKMRAB9A
SCHEMBL11787280 0.79 ANTXR2 (0.41) MEN1KMT2AANTXR2PKMRAB9A
SCHEMBL11790999 0.79 ELANE (0.38) MEN1KMT2AANTXR2PKMRAB9A
SCHEMBL11791759 0.75 ELANE (0.38) MEN1KMT2AANTXR2PKMRAB9A
SCHEMBL11792467 0.75 MEN1 (0.45) MEN1KMT2AANTXR2PKMRAB9A
SCHEMBL11793109 0.75 DAO (0.41) MEN1KMT2AANTXR2PKMRAB9A
SCHEMBL11787934 0.74 ELANE (0.38) MEN1KMT2AANTXR2PKMRAB9A
SCHEMBL11791917 0.74 GAA (0.38) MEN1KMT2AANTXR2PKMRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3931235-A FROM THE ALKALIMETAL SALT OF 4-HYDROXY-6-METHYL-2-PYRONE AND A THIOLSULFONATE THE DOW CHEMICAL COMPANY (US) 1976-01-06 US disclosed