Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | GAA | P10253 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
| ▸ | BCL2 | P10415 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | LIPE | Q05469 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11794239 | 0.84 | KMT2A (0.48) | MEN1KMT2AALDH1A1MAPTGAA | |
| SCHEMBL13442674 | 0.80 | KDM4E (0.42) | MEN1KMT2AALDH1A1MAPTGAA | |
| SCHEMBL6960232 | 0.80 | SMN1; SMN2 (0.42) | MEN1KMT2AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL7397801 | 0.79 | SMN1; SMN2 (0.54) | MEN1KMT2AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL11788874 | 0.77 | DAO (0.43) | MEN1KMT2AALDH1A1MAPTGAA | |
| SCHEMBL11791101 | 0.77 | ANTXR2 (0.46) | MEN1KMT2AALDH1A1MAPTGAA | |
| SCHEMBL11787842 | 0.76 | ALDH1A1 (0.45) | MEN1KMT2AALDH1A1MAPTGAA | |
| SCHEMBL11794883 | 0.75 | MEN1 (0.44) | MEN1KMT2AALDH1A1MAPTGAA | |
| SCHEMBL8535277 | 0.75 | BCL2 (0.38) | MEN1KMT2AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL6965057 | 0.75 | SMN1; SMN2 (0.46) | MEN1KMT2AALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3931235-A | FROM THE ALKALIMETAL SALT OF 4-HYDROXY-6-METHYL-2-PYRONE AND A THIOLSULFONATE | THE DOW CHEMICAL COMPANY (US) | 1976-01-06 | — | — | US | disclosed |