Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.74 |
| ▸ | MEN1 | O00255 | 2/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.74 |
| ▸ | MAPT | P10636 | 2/20 | 0.74 |
| ▸ | MITF | O75030 | 1/20 | 0.74 |
| ▸ | RAB9A | P51151 | 1/20 | 0.74 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.74 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | CPT1A | P50416 | 1/20 | 0.57 |
| ▸ | HTR4 | Q13639 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.55 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29950498 | 0.90 | LMNA (0.64) | LMNAMEN1KMT2AMAPTMITF | |
| SCHEMBL7385581 | 0.88 | LMNA (0.70) | LMNAMEN1KMT2AMAPTMITF | |
| SCHEMBL27273111 | 0.88 | MAPT (0.74) | LMNAMEN1KMT2AMAPTMITF | |
| SCHEMBL27908679 | 0.87 | NR4A2 (0.77) | LMNAMEN1KMT2AMAPTMITF | |
| SCHEMBL592889 | 0.87 | NR4A2 (0.77) | LMNAMEN1KMT2AMAPTMITF | |
| SCHEMBL2834218 | 0.86 | NR4A2 (0.75) | LMNAMEN1KMT2AMAPTMITF | |
| SCHEMBL8555897 | 0.85 | LMNA (1.00) | LMNAMEN1KMT2AMAPTMITF | |
| SCHEMBL3633587 | 0.84 | NR4A2 (0.73) | LMNAMEN1KMT2AMAPTMITF | |
| SCHEMBL5068806 | 0.84 | NR4A2 (1.00) | LMNAMEN1KMT2AMAPTMITF | |
| SCHEMBL1558974 | 0.83 | NR4A2 (0.71) | LMNAMEN1KMT2AMAPTMITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3980668-A | Anti-arrhythimic 5-endo-(3-indolecarbonyloxy)-N-[amino-(lower)alkyl]bicyclo[2,2,1]heptane-2,3-di-endo-carboxylic acid imides | BRISTOL-MYERS COMPANY (US) | 1976-09-14 | — | — | US | disclosed |
| US-3980667-A | Anti-arrhythmic 5-endo-substituted oxy-N-(aminoloweralkyl)bicycle [2.2.2.]oc | BRISTOL-MYERS COMPANY (US) | 1976-09-14 | — | — | US | disclosed |