Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8201328 | 0.88 | TP53 (0.59) | TP53ALDH1A1CYP3A4TDP1NLRP3 | |
| SCHEMBL9613901 | 0.88 | TP53 (0.43) | TP53ALDH1A1CYP3A4TDP1NLRP3 | |
| SCHEMBL11798133 | 0.88 | TP53 (0.54) | TP53ALDH1A1CYP3A4TDP1NLRP3 | |
| SCHEMBL11800654 | 0.87 | TP53 (0.51) | TP53ALDH1A1CYP3A4TDP1TSHR | |
| SCHEMBL11800610 | 0.86 | TP53 (0.38) | TP53ALDH1A1CYP3A4TDP1NLRP3 | |
| SCHEMBL11798583 | 0.83 | TP53 (0.41) | TP53GABRA1TSHRKDM4EHPGD | |
| SCHEMBL11796525 | 0.83 | TDP1 (0.51) | TP53ALDH1A1CYP3A4TDP1NLRP3 | |
| SCHEMBL28387927 | 0.81 | TP53 (0.63) | TP53ALDH1A1CYP3A4TDP1TSHR | |
| SCHEMBL11099540 | 0.76 | TP53 (0.58) | TP53ALDH1A1CYP3A4TDP1TSHR | |
| SCHEMBL10622917 | 0.75 | TP53 (0.59) | TP53ALDH1A1CYP3A4TDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3956388-A | N-methylol ethers of glycollic anilides | BASF AKTIENGESELLSCHAFT (DT) | 1976-05-11 | — | — | US | disclosed |