Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | XPO1 | O14980 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | GPX4 | P36969 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8200987 | 0.89 | TP53 (0.69) | TP53ALDH1A1TDP1CYP3A4MEN1 | |
| SCHEMBL8201328 | 0.88 | TP53 (0.59) | TP53ALDH1A1TDP1CYP3A4MEN1 | |
| SCHEMBL10667257 | 0.88 | TP53 (0.45) | TP53ALDH1A1TDP1CYP3A4MEN1 | |
| SCHEMBL10871245 | 0.87 | ALDH1A1 (0.48) | TP53ALDH1A1TDP1CYP3A4MEN1 | |
| SCHEMBL9292633 | 0.86 | ALDH1A1 (0.50) | TP53ALDH1A1TDP1CYP3A4MEN1 | |
| SCHEMBL8038076 | 0.86 | TP53 (0.70) | TP53ALDH1A1TDP1CYP3A4MEN1 | |
| SCHEMBL11122318 | 0.86 | TP53 (0.76) | TP53ALDH1A1TDP1CYP3A4MEN1 | |
| SCHEMBL9292342 | 0.85 | TP53 (0.58) | TP53ALDH1A1TDP1CYP3A4MEN1 | |
| SCHEMBL10661584 | 0.84 | ALDH1A1 (0.54) | TP53ALDH1A1TDP1CYP3A4MEN1 | |
| SCHEMBL10663763 | 0.84 | TP53 (0.54) | TP53ALDH1A1TDP1CYP3A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4296254-A | N-METHYLENE ETHER-2-HALOACETAMIDES, ACID CATALYST | MONSANTO COMPANY (US) | 1981-10-20 | — | — | US | claimed |
| EP-0053495-B1 | PROCESS FOR PRODUCING N-(HALOMETHYL) ACYLAMIDES | MONSANTO COMPANY (US) | 1984-08-08 | — | — | EP | disclosed |
| EP-0053495-A1 | Process for producing N-(halomethyl) acylamides | MONSANTO COMPANY (US) | 1982-06-09 | — | — | EP | disclosed |
| US-4311858-A | Process for producing N-(halomethyl) acyl-amides | MONSANTO COMPANY (US) | 1982-01-19 | — | — | US | disclosed |