Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.74 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11795403 | 1.00 | SIGMAR1 (0.74) | SIGMAR1HRH3KDM4EALDH1A1TAAR1 | |
| SCHEMBL11795413 | 1.00 | SIGMAR1 (0.74) | SIGMAR1HRH3KDM4EALDH1A1TAAR1 | |
| SCHEMBL3252059 | 0.85 | SIGMAR1 (1.00) | SIGMAR1 | |
| SCHEMBL3252058 | 0.85 | SIGMAR1 (1.00) | SIGMAR1 | |
| SCHEMBL3252055 | 0.85 | SIGMAR1 (1.00) | SIGMAR1 | |
| SCHEMBL18411348 | 0.84 | SIGMAR1 (0.53) | SIGMAR1HRH3 | |
| SCHEMBL11787517 | 0.76 | SIGMAR1 (0.69) | SIGMAR1HRH3TAAR1DAO | |
| SCHEMBL11787525 | 0.76 | SIGMAR1 (0.69) | SIGMAR1HRH3TAAR1DAO | |
| SCHEMBL11787522 | 0.76 | SIGMAR1 (0.69) | SIGMAR1HRH3TAAR1DAO | |
| SCHEMBL11785147 | 0.71 | SIGMAR1 (0.64) | SIGMAR1HRH3ALDH1A1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3962249-A | 1-(3-PHENYLPROPYL)-4-FUROYLPIPERAZINE DERIVATIVES | KYORIN SEIYAKU KABUSHIKI KAISHA (JA) | 1976-06-08 | — | — | US | disclosed |