Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | VCP | P55072 | 2/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 3/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.37 |
| ▸ | LIPC | P11150 | 1/20 | 0.37 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetanilide SCHEMBL11797057 | 0.87 | CA2 (0.41) | CA2KDM4EUSP2ALDH1A1LMNA | |
| Aniline SCHEMBL11796628 | 0.83 | CISD1 (0.52) | CA2KDM4EUSP2ALDH1A1LMNA | |
| Aniline SCHEMBL11809275 | 0.81 | CA2 (0.44) | CA2KDM4EUSP2ALDH1A1LMNA | |
| SCHEMBL11787527 | 0.81 | CA2 (0.43) | CA2KDM4EUSP2ALDH1A1LMNA | |
| Aniline SCHEMBL11799685 | 0.80 | CA2 (0.44) | CA2KDM4EUSP2ALDH1A1LMNA | |
| Aniline SCHEMBL11806717 | 0.80 | CA2 (0.43) | CA2KDM4EUSP2ALDH1A1LMNA | |
| SCHEMBL11791772 | 0.79 | CA2 (0.42) | CA2KDM4EUSP2ALDH1A1LMNA | |
| Aniline SCHEMBL11801565 | 0.79 | CA2 (0.40) | CA2KDM4EUSP2ALDH1A1LMNA | |
| SCHEMBL11784558 | 0.79 | KDM4E (0.57) | CA2KDM4EUSP2ALDH1A1LMNA | |
| SCHEMBL11796436 | 0.79 | KDM4C (0.37) | CA2KDM4EUSP2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3992440-A | DIURETICS | CIBA-GEIGY CORPORATION (US) | 1976-11-16 | — | — | US | disclosed |
| US-3982018-A | DIURETICS | CIBA-GEIGY CORPORATION (US) | 1976-09-21 | — | — | US | disclosed |