Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | P2RY4 | P51582 | 4/20 | 0.48 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | S100A4 | P26447 | 1/20 | 0.47 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.45 |
| ▸ | FABP3 | P05413 | 1/20 | 0.45 |
| ▸ | FABP4 | P15090 | 1/20 | 0.45 |
| ▸ | C1R | P00736 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.43 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.41 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | TOP2A | P11388 | 1/20 | 0.41 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11791498 | 0.87 | CXCL8 (0.48) | PTPN1P2RY4CXCL8CYP2C9S100A4 | |
| SCHEMBL11798486 | 0.83 | P2RY4 (0.46) | P2RY4P2RY12EGFRADORA2APGAM1 | |
| SCHEMBL11795610 | 0.83 | CXCL8 (0.47) | PTPN1P2RY4CXCL8CYP2C9S100A4 | |
| SCHEMBL17693661 | 0.78 | P2RY4 (0.61) | P2RY4P2RY2RAPGEF4HPGD | |
| SCHEMBL11790292 | 0.77 | FABP3 (0.48) | P2RY4S100A4MCL1EGFRFABP3 | |
| SCHEMBL11798532 | 0.75 | CYP1A2 (0.47) | P2RY4P2RY12ADORA2AP2RY2CYP1A2 | |
| SCHEMBL9846540 | 0.75 | MAPT (0.53) | P2RY4P2RY12ADORA2AP2RY2CYP1A2 | |
| SCHEMBL11063817 | 0.75 | DHODH (0.60) | P2RY4EGFRFABP3FABP4ADORA2A | |
| SCHEMBL17034602 | 0.74 | MAPT (0.46) | PTPN1P2RY4EGFRFABP3FABP4 | |
| SCHEMBL17029053 | 0.73 | DHODH (0.54) | P2RY4CXCL8EGFRFABP3FABP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3998780-A | Bis-(polyhalogenoanilino)-anthraquinones | CIBA-GEIGY CORPORATION (US) | 1976-12-21 | — | — | US | disclosed |