Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 2/20 | 0.42 |
| ▸ | DRD3 | P35462 | 2/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | MC4R | P32245 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29221145 | 0.88 | HPGD (0.42) | HPGDDRD1DRD3OPRM1CHRM2 | |
| SCHEMBL2611681 | 0.82 | CYP2D6 (0.49) | HPGDCYP2D6CHRM1KCNH2SMN1; SMN2 | |
| SCHEMBL16908176 | 0.80 | MAPT (0.46) | L3MBTL1TDP1SMN1; SMN2 | |
| SCHEMBL2207076 | 0.80 | DRD1 (0.38) | DRD1DRD3HTR2ASLC6A3DRD4 | |
| SCHEMBL10272984 | 0.80 | SMN1; SMN2 (0.40) | HPGDCYP2D6HTR2AHTR2CDRD2 | |
| SCHEMBL23749704 | 0.80 | ALDH1A1 (0.42) | POLB | |
| SCHEMBL2209593 | 0.80 | TSHR (0.41) | HPGDDRD1POLBTDP1TSHR | |
| SCHEMBL17447179 | 0.79 | HPGD (0.50) | HPGDTSHRSMN1; SMN2 | |
| SCHEMBL13205026 | 0.79 | HPGD (0.50) | HPGDTSHRSMN1; SMN2 | |
| SCHEMBL14433347 | 0.79 | HPGD (0.40) | HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3931196-A | Phosphinolines and phosphindolines | MONASH UNIVERSITY (AU) | 1976-01-06 | — | — | US | disclosed |